This report summarizes the latest information about COVID-19 and the Latino community in Los Angeles (L.A.) County, including the impact of the pandemic on this community, vaccinations, and other key successes and risks. The report draws on data from USC’s Understanding Coronavirus in America tracking survey (UAS, 2021), that has monitored COVID-19 related outcomes among a representative sample of approximately 1,800 adult L.A. County residents, including ≈43% Latinos. Panel participants have typically been surveyed every two weeks since March 2020. We also draw upon qualitative data collected by our research team through community meetings (N=3) and public townhalls (N=2) held with Latino residents and community stakeholders in East L.A from September 2020 to January 2021. Key findings are that Latinos in L.A. County have been more likely to get a COVID-19 infection and to suffer many of the negative secondary consequences of the pandemic. Although there is enthusiasm for getting the COVID-19 vaccine, much work remains to improve vaccine access and equity among Latinos, and to support their pandemic recovery.